Since rawr Goldfarming got nerfed to the ground it is all about farming the right mats. Watch some Youtube Videos and check the AH or TSM Website if it is worth farming. There are some pretty unknown yet very rewarding farming spots like Nether Dragon Scales https://www.tradeskillmaster.com/items/nether-dragonscales-29548. Also all kind of pets sell very well.
In case you got a decent graphic card you can also farm Bitcoins, Ethereum, ZCash etc. at the same time your Bots are running.