In settings / advanced setting there should be latency""... believe its 300-700 default? Reduce hat number down to around your game latency wand watch the bot for a bit. You may see it start to skip looting / skinning in which case bump it back up.. try find a good spot.
Quester.Bot > Pulse(): System.NullReferenceException: Object reference not set to an instance of an object. at Quester.Bot.Bot.Pulse(Boolean loadSettingsProfile, String profile)
You are loading the profile under the wrong type. AKA- you are trying to load a grind / farming profile in quester mode. check what mode the file should be loaded under and start it with that mode.